EN

师资队伍

赵晓丽Xiaoli Zhao

研究员 特聘教授

药学院

邮箱:zhao.xl@siat.ac.cn

研究领域

干细胞外泌体、损伤组织再生、可注射材料与器械、3D/4D打印、响应性只能材料研究领域

个人简介

研究员、博导,中科院特聘研究员,深圳市高层次人才。香港大学医学院博士毕业,美国约翰霍普金斯大学访问学者,研究领域主要针对骨与关节损伤组织损伤,主持科技部重点研发课题和国自然项目,承担和参与国家和省市级科研项目多项。相关研究在Nature Communication、Adv Mater,Adv Funct Mater,ACS Nano,Adv Sci等期刊上发表SCI文章50余篇,授权16项发明专利。国际矫形与创伤外科学会(SICOT)委员会委员,中国生物材料学会委员,中国老年学和老年医学学会委员。

学习工作经历

学习经历:

2007.09–2011.08,香港大学,医学院,骨科生物材料,博士

2010.11–2011.05,霍普金斯大学,骨分子生物学,访问

2005.09–2007.07,天津大学,生物医学工程,硕士

2001.09–2005.07,天津大学,高分子材料科学与工程,学士。

工作经历:

2021.12-至今,深圳理工大学,药学院,特聘教授。

2020.01-至今,中国科学院深圳先进技术研究院,生物医药与技术研究所,研究员。

2012.01-2019.12,中国科学院深圳先进技术研究院,生物医药与技术研究所,助理研究员,副研究员。

国际影响力

H-factor: 25;

SCI检索文章51篇,Total number of citations:2191;

国际矫形与创伤外科学会(SICOT)委员会委员

国际华人骨研协会会员

担任AdvancedMaterial,Advanced Functional material, Advanced Science,Bioactive materials等先进材料与再生技术领域主流SCI期刊的审稿人

香港Research Grants Council项目评审专家;

在WBC 11thWorld Biomaterials Congress, 29thAnnual Meeting of the European Society for Biomaterials, The 26thInterdisciplinary Research Conference on Injectable Osteoarticular Biomaterials and Bone Augmentation Procedures (GRIBOI),21stAnnual conference of ANZORS (Australian & New Zealand Orthopaedic Research Society)等国际会议上进行学术报告

所获荣誉

中科院特聘研究员

深圳市自然科学二等奖

2014,Sholarship of Australia–China Musculoskeletal Alliance.

2012,“Annual meeting Young Investigator Travel Grant”in 33rdAmerican Society for Bone and Mineral Research meeting

深圳市高层次人才

The Article of the Year Ward, (5/500), 2023,”Engineering Stem Cells to Produce Exosomes with Enhanced Bone Regeneration Effects: An Alternative Strategy for Gene Therapy. Journal of Nanobiotechnology, 2022:,20:135

科研成果

科技部重点研发,时序响应调控炎症组织微环境的抗菌促创面修复高分子水凝胶研制,2022-2025,课题三负责人。

科技部重点研发,功能组织与器官体外精准制造技术与重建,2019-2024,课题四任务负责人。

4D printed hydrogel scaffold with swelling-stiffening properties and programmable deformation for minimally invasive implantation,Nature Communication,2024,15:1587.(通讯作者SCI Q1,IF=16.6, Nature index收录期刊)

An injectable rapid-adhesion and anti-swelling adhesive hydrogel for hemostasis and wound sealing,Advanced Functional Materials,2022,32, 2207741.(通讯作者IF 19.0,Q1,Nature index,封面文章)

Antioxidative bioactive glass reinforced injectable hydrogel with reactive oxygen species scavenging capacity for diabetic wounds treatment,Chemical Engineering Journal, 2024,148768,(通讯作者,IF 15.1 Q1)

Bone Targeting miR-26a Loaded Exosome-Mimetics for Bone Regeneration Therapy by Activating Wnt Signaling Pathway.Chemical Engineering Journal,2023,471:144594(通讯作者,IF 15.1 Q1)

miR-204 ameliorates osteoarthritis pain by inhibiting SP1-LRP1 signaling and blocking neuro-cartilage interaction,Bioactive Materials,2023,26:425-436(通讯作者,IF18.9, Q1)

Engineering Stem Cells to Produce Exosomes with Enhanced Bone Regeneration Effects: An Alternative Strategy for Gene Therapy.Journal of Nanobiotechnology, 2022:,20:135(IF10.2,Q1,)

Bioinspired Multichannel Nerve Guidance Conduit Based on Shape Memory Nanofibers for Potential Application in Peripheral Nerve Repair.ACS Nano2020, 14, 12579−12595 ,2022 Oct (IF 17.1, Q1, Nature index收录期刊)

Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow,Nature Communication, 2024,15,3769.(IF=16.6,Q1,Nature index收录期刊)

A Unified Therapeutic-Prophylactic Tissue Engineering Scaffold Demonstrated to Prevent Tumor Recurrence and Overcoming Infection toward Bone Remodeling.Advanced Materials,2023, 2300313(IF 29.4, Q1,Nature index收录期刊)

Osteochondral Regeneration with 3D-Printed Biodegradable High-Strength Supramolecular Polymer Reinforced-Gelatin Hydrogel Scaffolds.Advanced Science, 2019,6(15): 1900867.IF 15.1, Q1,Nature index收录期刊, ESI高被引论文).

3D-Bioprinted Osteoblast-Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo,Advanced Science, 2018, 5(3): 1700550.IF 15.1, Q1,Nature index收录期刊).

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